Wahle A, Sonka M:


Coronary Plaque Analysis by Multimodality Fusion.

In:

Suri JS, Yuan C, Wilson DL, Laxminarayan S (eds):

Plaque Imaging: Pixel to Molecular Level.

Studies in Health, Technology and Informatics, IOS Press, Amsterdam

Volume 113, Page 321-359, 2005


Contents:

1.   Introduction
2.   Biplane Angiography
      2.1.  Acquisition and Preprocessing
2.2.  Geometry Estimation
    2.2.1.  Coordinate Systems
2.2.2.  The Epipolar Constraint
2.3.  3-D Reconstruction of the IVUS Trajectory
3.   Intravascular Ultrasound
3.1.  Acquisition and Preprocessing
3.2.  Segmentation
4.   Fusion of Angiography and IVUS
4.1.  Outline of the Fusion Process
4.2.  Localization of IVUS Frames on 3-D Path
4.3.  Catheter Curvature and Torsion
4.3.1.  The Frenet-Serret Formulas
4.3.2.  Analytical Model of the Catheter
4.3.3.  Estimation of the Relative Twist
4.3.4.  Estimation of the Absolute Orientation
4.4.  3-D Mapping of the IVUS Data
5.   Validation
5.1.  Description of Validation Setups
5.1.1.  Validations in Phantoms
5.1.2.  Cadaveric Pig Hearts
5.1.3.  In-Vivo Validation
5.2.  Validation Results
5.2.1.  Validations in Phantoms
5.2.2.  Clips Analysis
5.2.3.  Complete Fusion Cycle
5.2.4.  In-Vivo Validation
6.   Clinical Applications and Results
6.1.  3-D vs. 4-D Modeling
6.2.  Computational Hemodynamics
6.3.  Plaque Development and Vessel Geometry
6.4.  Simulation of Interventional Procedures
7.   Discussion and Conclusions