A Real-time 3-dimensional Digital Doppler Method for Measurement of Flow Rate and Volume Through Mitral Valve in Children: A Validation Study Compared with Magnetic Resonance Imaging

Shuping Ge, Liping Bu, Honghai Zhang, Erik Schelbert, Michelle Disterhoft, Xiangning Li, Xiaokui Li, David Sahn, Alan Stolpen, Milan Sonka

Journal of the American Society of Echocardiography, January 2005, Volume 18, Issue 1, pp. 1-7.

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Abstract

We developed and assessed a real-time 3-dimensional (3D) digital Doppler method for measurement of flow volumes through the mitral valve in children. A total of 13 children (aged 10.46+-2.5 years; 8 boys/5 girls) were enrolled. An ultrasound system (Sonos 7500, Philips, Andover, Mass) was used to acquire raw 3D velocity data for flow measurement based on Gaussian control surface theorem [flow (mL/s) = mean velocity x flow area]. Stroke volume (SV) measured by real-time 3D digital Doppler with the control surface at the mitral valve annulus or orifice was compared with the SV by phase velocity cine magnetic resonance imaging (MRI) at the ascending aorta and by left ventricular volumetric MRI measurement. The best correlation and agreement were seen at the mitral valve orifice by real-time 3D digital Doppler compared with SV by phase velocity cine MRI at the ascending aorta (r = 0.92, mean difference = -5.2 +- 12.0 mL) and SV by left ventricular volumetric MRI measurement (r = 0.94, mean difference = -0.2 +- 10.3 mL).

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Links

Journal of the American Society of Echocardiography

Notes

Associated labs/groups:
Department of Pediatrics, The University of Iowa
Department of Radiology, The University of Iowa

Text Reference

Shuping Ge, Liping Bu, Honghai Zhang, Erik Schelbert, Michelle Disterhoft, Xiangning Li, Xiaokui Li, David Sahn, Alan Stolpen, Milan Sonka, "A Real-time 3-dimensional Digital Doppler Method for Measurement of Flow Rate and Volume Through Mitral Valve in Children: A Validation Study Compared with Magnetic Resonance Imaging" Journal of the American Society of Echocardiography, January 2005, Volume 18, Issue 1, pp. 1-7.

BibTeX Reference

@article{Ge_2005_JASE,
  author = "Shuping Ge, Liping Bu, Honghai Zhang, Erik Schelbert, Michelle Disterhoft, Xiangning Li, Xiaokui Li, David Sahn, Alan Stolpen, Milan Sonka",
  title = "A Real-time 3-dimensional Digital Doppler Method for Measurement of Flow Rate and Volume Through Mitral Valve in Children: A Validation Study Compared with Magnetic Resonance Imaging",
  journal = " Journal of the American Society of Echocardiography",
  year = "2005",
  volume= "18",
  issue = "1",
  pages = "1-7"
}

The College of Engineering Imaging Group(CEIG) is part of the Department of Electrical and Computer Engineering, University of Iowa.